Semyon Tsyrenov is originally from Chita, Russia. As a junior, he competed in the Russian Juniors National Tournament and played ITF Junior tournaments across Europe.

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He had a goal to come to the United States to play college tennis after his brother came over to attend and play for Auburn University. Semyon played for Rockhurst University where he reached as high as #10 in the NCAA Division II national singles rankings. He won the Midwest Region Championship in 2024, and in 2025 became the first All-American in program history. He also helped his team reach the GLVC Championship Final and the second round of the NCAA Division II National Championships. In 2025, he was named Rockhurst University Male Student-Athlete of the Year. ​